Health & Medicine

1. Blood tests reveal why astronauts get constipated in space

   Spaceflight may dramatically change the gut within weeks, causing bacteria to break down more protein as food moves more slowly through the intestines. The shift could help explain astronaut constipation and may have wider effects on health, making it an important concern for future missions to Mars.

2. Scientists find new virus behind mysterious tick illness

   Scientists have discovered a new tick-borne virus in China that causes flu-like illness and may account for previously unexplained cases of fever, fatigue, digestive problems, and low platelet counts. Most patients with ALTNV alone recovered, but coinfections with another dangerous tick-borne virus were linked to more serious complications.

3. Diabetes study finds keeping blood sugar too steady may come at a price

   People with diabetes reported better quality of life after days when their glucose stayed largely within a healthy range, even when levels fluctuated more than usual. The unexpected finding suggests that pursuing extremely tight glucose control may sometimes come with a hidden lifestyle burden.

4. Hidden stem cells may be fueling spinal stenosis

   Scientists have discovered a stem cell that appears to serve as a master source for tendon and ligament cells throughout the body. In lumbar spinal stenosis, these cells become unusually active and may drive the ligament overgrowth that squeezes spinal nerves and causes pain, numbness, and difficulty walking. Researchers found that reducing calcium signaling stopped this abnormal growth in mice.

5. Scientists just discovered what coffee really does to your gut and brain

   A new study suggests coffee may influence mood and brain function by changing the activity of microbes in the gut. Both caffeinated and decaf coffee were linked to lower stress, depression, and impulsivity, while also producing measurable changes in gut bacteria and metabolites. Decaf was associated with better learning and memory, while caffeinated coffee appeared to reduce anxiety and improve attention.

6. Glucosamine, a popular joint supplement, linked to faster Alzheimer’s progression

   A large health-record analysis found that glucosamine use was associated with a 25% higher likelihood of mild cognitive impairment progressing to dementia. Lab experiments suggest the popular joint supplement may intensify an abnormal sugar-tagging process in the Alzheimer’s brain, although researchers say clinical trials are needed to determine whether it actually causes harm.

7. Zepbound and Mounjaro may turn on the body’s calorie-burning brown fat

   Tirzepatide, sold as Mounjaro and Zepbound, activated calorie-burning brown fat in obese mice, revealing a potential metabolic effect beyond appetite suppression. If confirmed in humans, the finding could help explain the drug’s powerful benefits and inspire more comprehensive treatments for obesity and diabetes.

8. Why rheumatoid arthritis pain may persist even when inflammation is under control

   Pain and fatigue in rheumatoid arthritis can persist even after inflammation improves, with depression, poor sleep, obesity, smoking, and chronic pain potentially helping sustain symptoms. Researchers say identifying these hidden drivers could prevent unnecessary medication changes and lead to more personalized treatment.

9. Pomegranate compound improves heart function by up to 80% in study

   A compound the body can make after eating pomegranates, walnuts, and some berries improved measures of heart function by up to 80% in animal models of a difficult-to-treat form of heart failure. Urolithin A helped stiff heart tissue relax and reduced scarring and abnormal enlargement. It also improved relaxation in engineered human heart tissue.

10. 160-million-year-old proteins show surprising power against superbugs

    Scientists resurrected antimicrobial peptides from mammals that lived millions of years ago and found that some were more potent against drug-resistant bacteria than modern human versions. These evolutionary relics could provide new clues for designing treatments as antibiotic resistance becomes an increasingly serious threat.

11. That fresh cleaning smell could be filling your home with nanoparticles

    Researchers found that scented cleaners can react with ozone indoors to create billions or trillions of invisible nanoparticles that can penetrate deep into the lungs. The pollution forms within minutes and, in some cases, may produce an inhaled particle dose comparable to or greater than standing near heavy traffic.

12. Scientists found a surprising driver of Alzheimer’s outside the brain

    Scientists found that immune cells contributing to Alzheimer’s-related brain damage may be activated in lymph nodes outside the brain before traveling into the nervous system. Blocking this pathway in mice dramatically reduced neurodegeneration and preserved cognitive abilities, pointing to a potentially more accessible treatment target.

13. Atrial fibrillation patients saw 69% lower risk with common blood thinners

    Direct oral anticoagulants cut the risk of serious clinical events by 69% in atrial fibrillation patients with an intermediate risk of stroke, according to the randomized SINGLE-AF trial. The benefit was driven mainly by fewer ischemic strokes, with no increase in major bleeding.

14. One CRISPR treatment cut “bad” cholesterol in half for a full year

    A single dose of an experimental CRISPR therapy cut LDL cholesterol and triglycerides by about half in patients with difficult-to-treat lipid disorders. The reductions were still present one year later, with the highest dose lowering LDL by 52.5% and triglycerides by 47.8%.

15. Scientists say house cats could help unlock better cancer treatments for humans

    Scientists have mapped the genetics of cat cancer on an unprecedented scale and found surprising similarities with tumors in humans. The findings could help bring precision cancer treatments to cats while also revealing new clues about how human cancers develop and respond to drugs.